KONAKION MM 2 mg solution, 5 pcs

Instructions for use for KONAKION MM 2 mg solution, 5 pcs

Field of use

• The preparation is a vitamin to prevent bleeding (anti -hemorrhagic).
• The medicine is used to prevent and treat vitamin K deficiency bleeding in newborns.

Active ingredients / ingredients / ingredients

2 mg phytomenadion
3-sN phosphatidylcholine (soybean) Hedge substance (+)
Glycocholic acid auxiliary material (+)
Sodium hydroxide auxiliary substance (+)
Salic acid, concentrated auxiliary material (+)
Water, for injection purposes auxiliary material (+)

Contradictions

• The medicine must not be used,
  • if your child is allergic to phytoma adion (vitamin K1) or one of the other components of this drug.

dosage

• Always apply this medicine as described or exactly according to the consultation made with your doctor, pharmacist or the medical staff. Ask your doctor, pharmacist or medical staff if you are not sure.
• The following information applies unless your doctor prescribed the preparation.
• Prevention of a vitamin K deficiency bleeding
  • Healthy newborns who were born to or close to the calculated date of birth
  • These newborns receive either:
    • a one -time injection of 1 mg at birth or shortly after birth, or
    • a first dose of 2 mg by dropping into the mouth (oral) at birth or shortly after birth. This dose follows a second dose of 2 mg after 4 - 7 days and a third dose of 2 mg after 1 month. In infants that are fed exclusively with artificial infant food, the third dose can be omitted.
  • Newborns with a special risk of bleeding that were born prematurely or for the calculated date of birth (e.g. newborns with breathing nympia at birth; newborns with inflammatory and/or by disturbing biliary formation and the biliary flow conditional [cholestatischer] liver function; newborns who cannot swallow; newborns; Mothers treated with anticoagulant drugs [Antikoagulanzien] or means to treat seizures [Antiepileptika] )
    • These newborns receive Konakion mm 2 mg as injection at or shortly after birth.
    • Further injections can follow later if there is still a bleeding risk for your child.
  • More doses:
    • Newborns, who are preserved vitamin K by dropping into the mouth (orally) and which are breastfed (i.e. no artificial baby food received), can need more than three orally given vitamin K cans.
    • Newborns who receive bottle food and who have received two vitamin K cans will probably not need any further vitamin K cans, since vitamin K is already included in artificial infant food.
• Treatment of a vitamin K deficiency bleeding
  • Initial dose: 1 mg phytomenadion (corresponding to 0.1 ml solution) for ripe born or 0.4 mg/kg body weight (corresponding to 0.04 ml/kg body weight) in early born intravenous; If necessary, further gifts depending on the clinical image and the coagulation status. The treatment with the drug may have to be supported by additional measures, such as the transfusion of thoroughbred or coagulation factors in order to compensate for severe blood losses and the delayed response to vitamin K₁.
• Please speak to your doctor or pharmacist if you have the impression that the effect of the drug is too strong or too weak.

 

• If you have used a larger amount than you should
  • So far, no effects of an overdose are known.

 

• If you have any further questions about the application of this medicinehave TTELs, contact your doctor, pharmacist or the medical staff.

Taking

• The medicine is either dripped into the mouth or intrauscular or intravenously (i.e. by injection into the muscle or in the vein).
• The type of application depends on what the medicine is used for and whether your child was born early.
• Oral administration
  • The clear solution will be added directly to the infant's mouth.
• Parenteral administration
  • The preparation must not be diluted or mixed with other parenterals to be applied.
  • The intravenous administration of the drug must be carried out particularly slowly in order to ensure the strong possible dilution of the injection solution with the bloodstream.

Patient information

• Warnings and Precautions
  • Please speak to your doctor, pharmacist or the medical staff before using the medicine.
  • If possible, the solution for prevention in newborns should be administered intramuscularly, since the intravenous administration is connected to a temporary humiliation of the extent of the protein binding of bilirubin in the blood. This bilirubin, which is no longer bound to protein, is fat -soluble and can damage nerve cells in the brain (core dicerus). In general, if necessary, the dose of 0.4 mg phytomenadion per kg of body weight (corresponding to 0.04 ml solution per kg body weight) should not be exceeded and monitoring should not be exceeded due to the potential risk of developing a core icerus (a special disease of the brain). The plasma level of indirectly reacting bilirubin in Ikterische newborns.

Pregnancy

no information available

Hints

Miscellaneous

The nutritional commission of the German Society for Pediatrics recommends:-All children receive vitamin K prophylaxis to prevent later vitamin K deficiency bleeding. Further vitamin K income (2mg) takes place at U2 and U3. This second and third vitamin K intake is indispensable in children who are fully breastfed or with self-prepared cow milk food. Vitamin K1 as an injection (in the muscles or under the skin). Further vitamin K revenues are necessary to prevent the late vitamin K deficiency bleeding. The amount and type of application (2mg as a tablet in U2 and U3 as in healthy infants or repeated vitamin K injections) are carried out depending on the condition. An increase in the bile dye values (bilirubin) in the blood. Consideration and covers of vitamin K1:- Vitamin K1 can mainly be found in green leaves of different cabbage types, nettles, lucerne and spinach, as well as in fruits such as tomatoes, strawberries and rose hips, in muscle meat and liver, Milk and eggs. - The need is plentiful by daily food. For example, per 100g tomatoes are up to 400mg, in lettuce up to 700mg, in liver up to 600mg vitamin K1. Significations of deficiency:-Vitamin K deficiency symptoms can either be used by a real lack of vitamin K (e.g. due to nutritional or low absorption from the intestine) or in the treating use of Coagulation inhibitors (cumarinians) or by various inhibitors of the vitamin K1 epoxid reductase are caused. They express themselves through bleeding complaints such as bruises, blood in the feces, bloody urine and bleeding in the brain and spinal cord. - Taking the mother's coagulation inhibitors during pregnancy and breastfeeding early and lack of birth- Complicated birth- later feeding- exclusive breast milk nutrition- Inadequate feeding of infant, older child and adult:- Disease picture as a result of a disturbance of digestive food from the intestine (painting absorpion Syndrome)- Nutrition with bypass of gastrointellia- pancreatic diseases- treatment with antibiotics, especially with cephalosporins and sulfonamides or salicylates

Manufacturer:  CHEPLAPHARM Arzneimittel GmbH, Bahnhofstrasse 1a, 17498 Mesekenhagen