IBUPROFEN AbZ 20 mg/ml syrup, 100 ml

Instructions for use for IBUPROFEN AbZ 20 mg/ml syrup, 100 ml

Application notes

Infants from 6-8 months (with 5-6 kg body weight)	2.5 ml	1-3 times a day (max. 7.5 ml per day)	At a distance of 6 hours, at the meal
Infants from 9-11 months (with 7-9 kg body weight)	2.5  ml	1-4 times a day (max. 10  ml per day)	at a distance of 6 hours, at the meal
Small children from 1-3 years (with 10-15 kg body weight)	5  ml	1-3 times a day (max. 15  ml per day)	at a distance of 6 hours, at the meal
Children from 4-6 years (with 16-20 kg body weight)	7.5  ml	1-3 times a day (max. 22.5  ML per day)	at a distance of 6 hours, at the meal
Children from 7-9 years (with 21-29 kg body weight)	10-  ml	1-3 times a day (Max. 30  ML per day)	at a distance of 6 hours, at the meal

Application areas

Mode of action

How does the ingredient of the medicine work?

The active ingredient belongs to a group of fabrics that act against pain and inflammation and lower fever. All three effects are mainly based on the inhibition of a body's own fabric, called prostaglandin. This substance must be available as a messenger material so that pain is felt, inflammatory reactions can be started or body temperature can be increased.

Composition

Contradictions

What speaks against an application?

Always:
- Hypersensitivity to the ingredients
- Ulcers in the digestive tract, also in the frontlayer
- Active bleeding, like:
- Brain bleeding
- Bleeding in the gastrointestinal tract, also in the history

Under certain circumstances - speak to your doctor or pharmacist:
- Gastrointestinal complaints
- Inflammatory bowel diseases, also in history, such as:
- Crohn's disease
- Ulcerosa colitis
- Blood formation disorders
- Blood clotting disorder
- High blood pressure
- Heart failure
- Coronary heart disease (circulatory disorders of the heart muscle)
- Possible risk of narrowing of vascular narrowing, as with:
- Increased fat concentration in the blood
- Diabetes mellitus (diabetes)
- Smoking
- Circulatory disorders of the periphery (e.g. arms, legs)
- Circulatory disorder of the brain vessels
- Limited kidney function
- Restricted liver function
- Collagenoses (changes in the connective tissue area), such as:
- Lupus erythematodes
- Mixed collagenosis (inflammatory rheumatic collagenosis)
- Porphyria (metabolic disease)
- Larger operation, took place shortly before
- Chickenpox

Which age group must be observed?
- Infants under 6 months: The drug must not be used.
- Children aged 9 years old: The drug should generally not be used in this group. There are preparations that are more suitable from the active ingredient strength and/or dosage form.
- Older patients aged 65 and over: The treatment should be well coordinated with your doctor and carefully monitored, e.g. by close controls. The desired effects and undesirable side effects of the medicinal product can occur in this group increased or weakened.

What about pregnancy and lactation?
- Pregnancy: Contact your doctor. Various considerations play a role in whether and how the medicine can be used during pregnancy.
- Still -time: Contact your doctor or pharmacist. He will check your special starting position and advise you accordingly whether and how you can continue with breastfeeding.

If the medicine has been prescribed to you despite a counter -notification, speak to your doctor or pharmacist. The therapeutic benefit can be higher than the risk of using the application.

Side effects

What adverse effects may occur?

- Gastrointestinal complaints, such as:
- Nausea
- Vomiting
- Heartburn
- Flatulence
- Diarrhea
- Constipation
- Stomach pain
- Bleeding in the gastrointestinal area
- Tea chairs, if you appear, please see a doctor immediately
- Gastric mucosal inflammation
- Ulcers in the digestive tract, which can very rarely break through
- Headache
- Dizziness
- Fatigue
- Insomnia
- Irritability
- Excitement
- Super sensitivity reactions of the skin, such as:
- Skin rash
- Itching
- Breath of breathing diseases
- Visual disturbances, please see a doctor immediately if you occur

If you notice a disorder or change during treatment, contact your doctor or pharmacist.

For information at this point, side effects are taken into account that occurs in at least one of 1,000 patients treated.

Hints

What should you consider?
- The reaction capacity can also be impaired in the event of intended use, especially in higher doses or in combination with alcohol. Especially make sure that you take part in road traffic or operate machines (also in the household) with which you can injure yourself.
- Do not apply longer for pain or fever without medical advice than specified in the package insert!
- With permanent use of pain relievers, headaches can occur, which are generated by the pain reliever. Talk to your doctor to prevent your headache from becoming chronic.
- The habitual use of painkillers can lead to permanent kidney damage. If several pain relievers are combined, or if there are several active ingredients in a pain reliever, the risk increases.
- Caution: Patients with nasal polyps, chronic respiratory infections, asthma or with a tendency to allergic reactions such as hay fever: The medicine can have an AStrigger thma. or a strong allergic skin reaction. Therefor consult your doctor before usage.
- Beware of allergy to painkillers!
- Be careful with allergy against the sweetener saccharin (E 954)!
- Beware of an intolerance to glucose. If you have to adhere to a diabetes diet, you should take the sugar content into account.
- Beware of an intolerance to sucrose. If you have to adhere to a diabetes diet, you should take the sugar content into account.
- There can be medicinal products with which interactions occur. Therefore, you should generally provide the doctor or pharmacist before treatment with a new medicine. This also applies to medicines that you buy yourself, only apply occasionally or that the application has been available for some time.
- Alcohol enjoyment should be avoided as far as possible during an permanent treatment . Occasionally alcohol consumption in small quantities is allowed, but not together with the medication.

Detailed instructions for IBUPROFEN AbZ 20 mg/ml syrup, 100 ml

Field of use

• The preparation is an anti-inflammatory, fever-lowering and analgesic drug (non-steroidal anti-phlogistics/anti-rheumatic, NSAID).
• Application areas:
• The medicine is used for brief symptomatic treatment
  • slight to moderate pain
  • Fever

 

Active ingredients / ingredients / ingredients

100 mg ibuprofen
Citronic acid 1-water auxiliary material (+)
450 mg glucose auxiliary substance (+)
Polysorbate 80 HILDVERSTOFT (+)
Saccharin, sodium salt auxiliary material (+)
1 g sucrose auxiliary substance (+)
Water, cleaned auxiliary material (+)
Xanthan rubber auxiliary substance (+)
Potassium sorbat auxiliary substance (+)
115 mg total sodium ion helper (+)
Total sodium ion helper (+)
Strawberry aroma Hedge substance (+)
Aroma fabrics, natural and natural identical auxiliary substances (+)
9.2 mg propylene glycol auxiliary material (+)
Sahne aroma hedge material (+)
Aroma fabrics, natural and natural identical auxiliary substances (+)
Propylen glycol auxiliary substance (+)
Triacetin auxiliary substance (+)
0.4 mg benzyl alcohol auxiliary material (+)

Contradictions

• Ibuprofen must not be taken,
  • if your child is allergic to ibuprofen or one of the other components of this drug;
  • if your child has reacted in the past with bronchospasm, asthma attacks, nasal mucosal swelling, skin reactions or sudden swelling after taking acetylsalicylic acid or other non-steroidal inflammatory inhibitors
  • in the case of unexplained blood formation disorders;
  • in the event of existing or repeated stomach/duodenum ulcers (peptic ulcers) or bleeding (at least two different episodes of demonstrated ulcers or bleeding);
  • in the case of gastrointestinal bleeding or breakthrough (perforation) in the history in connection with previous therapy with non-steroidal anti-rheumatics/anti-inflammatory drugs (NSAID);
  • for brain bleeding (cerebrovascular bleeding) or other active bleeding;
  • in severe liver or kidney dysfunction;
  • with severe heart failure (heart failure);
  • in the case of severe dehydration (caused by vomiting, diarrhea or inadequate fluid intake);
  • in the last third of the pregnancy.

dosage

• Always take this medicine exactly as described here or exactly after the agreement made with your doctor or pharmacist. Ask your doctor or pharmacist if you are not sure.
• If this medicine is required for more than 3 days or if the symptoms worsen in children, medical advice should be obtained.
• Recommended dose is:
  • 5 - 6 kg (infants: 6 - 8 months)
    • Single dose: 2.5 ml (corresponding to 50mg ibuprofen)
    • max. Daily dose: 7.5 mll (corresponding to 150 mg ibuprofen)
  • 7 - 9 kg (children: 9 - 11 months)
    • Single dose: 2.5 ml (corresponding to 50 mg ibuprofen)
    • max. Daily dose: 10 ml (corresponding to 200 mg ibuprofen)
  • 10 - 15 kg (children: 1 - 3 years)
    • Single dose: 5 ml (corresponding to 100 mg ibuprofen)
    • max. Daily dose: 15 ml (corresponding to 300 mg ibuprofen)
  • 16 - 20 kg (children: 4 - 6 years)
    • Single dose: 7.5 ml (corresponding to 150 mg ibuprofen)
    • max. Daily dose: 22.5 ml (corresponding to 450 mg ibuprofen)
  • 21 - 29 kg (children: 7 - 9 years)
    • Single dose: 10 ml (corresponding to 200 mg ibuprofen)
    • max. Daily dose: 30 ml (corresponding to 600 mg ibuprofen)
• If you have taken the maximum single dose, wait at least 6 hours until the next income.
• The lowest effective dose should be used for the shortest duration required to relieve the symptoms.
• If you have an infection, consult a doctor immediately if the symptoms (e.g. fever and pain) stop or worsen.
• Dosage in older people:
  • No special dose adjustment is required.

 

• If you have taken a larger amount of ibuprofen than you should,
  • If you have taken more ibuprofen than you should, or if children have accidentally taken the medicine, always contact a doctor or a hospital near you to get an assessment of the risk and advice for further treatment.
    • The symptoms of overdose can include nausea, stomach pain, vomiting (possibly also with blood), headache, sausage of the ears, confusion and eye tremors. Bleeding in the gastrointestinal tract is also possible. At high doses, over sleepiness, drowsiness, chest pain, palpitations, fainting, cramps (especially in children), weakness and dizziness, blood in urine, functional disorders of liver and kidneys, reduced breathing (respiratory depression), blood pressure drop in skin and Mucous membranes (cyanosis), freezing and breathing problems reports.
    • There is no specific antidote (antidot).

 

• If you forgot to take it:
  • Do not take the double amount if you have forgotten the prior intake.

 

• If you have any further questions about the application of this medicine, please contact your doctor or pharmacist.

Taking

• Take ibuprofen according to the instructions of the doctor or according to the dosage instructions specified in the package insert. If you have the feeling that you do not feel sufficient pain relief, then do not increase the dose independently, but ask your doctor.
• For patients who have a sensitive stomach, it is advisable to take the Arneometer during meals.

Patient information

• Warnings and Precautions
  • Please speak to your doctor or pharmacist before your child takes the preparation.
  • Side effects can be minimized if the lowest effective effective dose required for symptom control is used over the shortest possible period.
  • Security in the gastrointestinal tract
    • Simultaneous use of the preparation with other non-steroidal inflammatory inhibitors including so-called COX-2 inhibitors (cyclooxygenase-2-inhibitors) should be avoided.
  • Older patients
    • In older patients, side effects occur more frequently after using NSAR, in particular bleeding and breakthroughs in the stomach and intestinal area, which may be life-threatening. Therefore, particularly careful medical monitoring is required in older patients.
  • Bleeding of the gastrointestinal tract, ulcers and breakthroughs (perforations)
    • Bleeding of the gastrointestinal tract, ulcers and perforations, also with a fatal outcome, were reported during treatment with all NSAIDs. They occurred with or without prior warning symptoms or serious events in the gastrointestinal tract in the prehistory at any time of therapy.
      • The risk of the occurrence of gastrointestinal bleeding, ulcers and breakthroughs is higher with climbender NSAR dose, in patients with ulcers in history, especially with the complications bleeding or breakthrough (the section can be found in the "contraindication" category), and in older patients. These patients should begin treatment with the lowest available dose. For these patients as well as for patients who accompanying low-dose acetylsalicylic acid (ASA) or other medicines that can increase the risk of gastrointestinal diseases, a combination therapy with gastric mucosa-protecting drugs should be (e.g. misoprostol or proton pump inhibitors).
      • If patients have a prehistory of side effects on the gastrointestinal tract, especially at older age, any unusual symptoms in the abdomen (especially gastrointestinal bleeding) should be reported, especially at the beginning of the therapy.
      • Caution is advisable if patients receive medicinal products at the same time that can increase the risk of ulcers or bleeding, such as: B. Oral corticosteroids, anti-blood clotting drugs such as warfarin, selective serotonin reuptake inhibitors, which are used, among other things, to treat depressive moods, or thrombocyte aggregation inhibitors such as ASA (the section can be found in the "Interactions" category).
      • If there is gastrointestinal bleeding or ulcers during treatment with ibuprofen, the treatment must be discontinued.
      • In patients with a gastrointestinal disease in the prehistory (ulcerative colitis, Crohn's disease), caution should be used because their condition can deteriorate (the section can be found in the "Side effects" category).
  • Effects on the cardiovascular system
    • Anti -inflammatory agents/painkillers such as ibuprofen can go hand in hand with a slightly increased risk of heart attack or stroke, especially when using in high doses. Do not exceed the recommended dose or duration of treatment (3 days).
    • You should discuss your treatment with your doctor or pharmacist before taking ibuprofen if you:
      • having heart disease, including heart failure (heart failure) and angina (chest pain), or a heart attack, a bypass operation, a peripheral arterial disease (circulatory disorders in the legs or feet due to the narrowed or closed arteries) or any kind of stroke (including mini-lag attack or transitory ischemic attack, "tia").
      • Heavy prints, diabetes or high cholesterol levels or heart diseases or strokes occur in their family history or when they are smokers.
  • Skin reactions
    • Serious skin reactions were reported in connection with treatment with ibuprofen. If the rash occurs, lesions of the mucous membranes, bubbles or other signs of an allergy should be adjusted to treatment with preparation and immediately go into medical treatment, as this can be the first signs of a very serious skin reaction (see category "Side effects").
    • During a chickenpox infection (varicella infection), an application should be avoided.
  • Infections
    • the medicine can cover signs of infections such as fever and pain. Therefore, it is possible that the drug is delayed by the drug, which can lead to an increased risk of complications. This was observed in bacterial pneumonia and bacterial skin infections in connection with chickenpox.
    • If you take this medicine during an infection and stop or worsen your symptoms of infection or worsen, consult a doctor immediately.
  • Other information
    • The preparation should only be used with the strict weighing of the benefit-risk ratio:
      • for certain innate blood formation disorders (e.g. acute intermittent porphyria);
      • for certain autoimmune diseases (systemic lupus erythematosus and mixed collagenosis).
  • A particularly careful medical monitoring is required:
    • with limited Kidney or liver function;
    • in dehydration;
    • directly after larger surgical interventions;
    • in allergies (e.g. skin reactions to other medicinal products, asthma, hay fever), chronic nasal mucosal swelling or chronic respiratory diseases narrowing.
  • Severe acute hypersensitivity reactions (e.g. anaphylactic shock) are very rarely observed. At the first sign of a severe hypersensitivity reaction after taking ibuprofen, the therapy must be canceled. The symptoms corresponding, medically required measures must be initiated by expert persons.
  • Ibuprofen can temporarily inhibit the platelet function (thrombocyte aggregation). Patients with blood clotting disorders should therefore be carefully monitored.
  • If the drug is used for a long time, regular control of the liver values, the kidney function and the blood count is required.
  • When taking ibuprofen before surgical interventions, the doctor or dentist must be questioned or informed.
  • The longer use of all kinds of painkillers against headaches can make them worse. If this is the case or if this is suspected, medical advice should be obtained and treatment can be broken off. The diagnosis of headache in medication overuse (Medication Overuse Headache, MOH) should be assumed in patients who suffer from frequent or daily headaches, although (or precisely because) they regularly take medicines for headaches.
  • In general, the habitual intake of pain relievers, especially when combining several pain relieving active ingredients, can lead to permanent kidney damage with the risk of kidney failure (analgesic nephropathy).
  • Children
    • There is a risk of kidney dysfunction in dehydrated children.
    • An application of ibuprofen in children under 6 months is not recommended, since there is no sufficient experiences for this.

 

• Wateriness and ability to operate machines
  • Since when using ibuprofen in higher dosage, central nervous side effects such as tiredness and dizziness can occur, the reaction capacity can be changed in individual cases and the ability to actively participate in road traffic and to operate machines can be impaired. This applies even more in combination with alcohol. You can then no longer react quickly and specifically to unexpected and sudden events. In this case, do not drive a car or other vehicles. Do not operate any tools or machines. Do not work without a safe grip.

Pregnancy

• If you are pregnant or breastfeed, or if you suspect that you are pregnant or intend to become pregnant, ask your doctor or pharmacist for advice before taking this drug.
• Pregnancy:
  • If pregnancy is determined during the application of ibuprofen, the doctor must be notified. You may only take the Arneometer in the first and second third of pregnancy after consultation with your doctor. In the last third of pregnancy, ibuprofen may not be taken due to an increased risk of complications for mother and child.
• Breastfeeding
  • The active ingredient ibuprofen and its dismantling products only pass into breast milk in small quantities. Since adverse consequences for the infant have not yet become known, an interruption of breastfeeding will generally not be necessary if the recommended dose is used.
• Reproductive ability
  • The preparation belongs to a group of medicinal products (non-steroidal anti-rheumatics) that can affect the fertility of women. This effect is reversible after stopping the drug (reversible).

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